top of page

PUBLICATIONS

markus-spiske-XrIfY_4cK1w-unsplash_edite

15. Vaishnavi, S.; Mesa, C.; Ellipilli, S*. RNA Interference-Based Therapeutics as Next Generation Drugs. Proc. Indian Natl. Sci. Acad. 2026, (DOI:10.1007/s43538-026-00908-6)

14. Vishwakarma, J.;  Suryawanshi, M. B.;  Takkella, D.;  S, A. K.;  Dhiman, S.;  Sappati, S.;  Gavvala, K*.; Ellipilli, S*., Photophysical tuning of fluorinated benzimidazole fluorophores: Donor-acceptor systems and BSA interactions. Bioorg. Chem., 2026, 181, 110340. DOI: 10.1016/j.bioorg.2026.110340

13. Vaishnavi, S.; Ellipilli, S*. Chapter: The Trials and Tribulations of the microRNA Therapy Market. Book: microRNA Modulation: A Promising Combination Therapy for Cancer. Springer Nature Singapore, 2026; pp 371–394. DOI: 10.1007/978-981-95-5989-3_17

12. Vaishnavi, S.;  Bhatt, C. S.; Ellipilli, S*., Multigene RNAi Technology to Treat Cancer: Harnessing Synergistic Gene Regulation to Combat Evolving Cancer. Mol. Pharm., 2025, 22 (11), 6472-6498. DOI: 10.1021/acs.molpharmaceut.5c00733

11. Takkella, D.;  Suryawanshi, M. B.;  Mani, M.;  Ellipilli, S*.; Gavvala, K*., Carbazole-rhodanine conjugate acts as an effective fluorescence biomarker for protein structural dynamics studies. Int. J. Biol. Macromol., 2025, 323, 147156. DOI: 10.1016/j.ijbiomac.2025.147156

10. Kurakula, H.;  Vaishnavi, S.;  Sharif, M. Y.; Ellipilli, S*., Emergence of Small Interfering RNA-Based Gene Drugs for Various Diseases. ACS Omega, 2023, 8 (23), 20234-20250. DOI: 10.1021/acsomega.3c01703

9. Ellipilli, S.;  Wang, H.;  Binzel, D. W.;  Shu, D.; Guo, P., Ligand-displaying-exosomes using RNA nanotechnology for targeted delivery of multi-specific drugs for liver cancer regression. Nanomedicine, 2023, 50, 102667. DOI: 10.1016/j.nano.2023.102667

8. Ellipilli, S.;  Wang, H.;  Lee, W. J.;  Shu, D.; Guo, P., Proof-of-concept for speedy development of rapid and simple at-home method for potential diagnosis of early COVID-19 mutant infections using nanogold and aptamer. Nanomedicine, 2022, 45, 102590. DOI: 10.1016/j.nano.2022.102590

7. Binzel, D. W.;  Li, X.;  Burns, N.;  Khan, E.;  Lee, W. J.;  Chen, L. C.;  Ellipilli, S.;  Miles, W.;  Ho, Y. S.; Guo, P., Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine-Specific Cancer Targeting with Undetectable Toxicity. Chem. Rev., 2021, 121 (13), 7398-7467. DOI: 10.1021/acs.chemrev.1c00009

6. Wang, H.;  Ellipilli, S.;  Lee, W. J.;  Li, X.;  Vieweger, M.;  Ho, Y. S.; Guo, P., Multivalent rubber-like RNA nanoparticles for targeted co-delivery of paclitaxel and MiRNA to silence the drug efflux transporter and liver cancer drug resistance. J. Control. Release, 2021, 330, 173-184. DOI: 10.1016/j.jconrel.2020.12.007

5. Ayele, T. M.;  Knutson, S. D.;  Ellipilli, S.;  Hwang, H.; Heemstra, J. M., Fluorogenic Photoaffinity Labeling of Proteins in Living Cells. Bioconjug. Chem., 2019, 30 (5), 1309-1313. DOI: 10.1021/acs.bioconjchem.9b00203

4. Ellipilli, S.;  Phillips, J. D.; Heemstra, J. M., Synthesis of comb-shaped DNA using a non-nucleosidic branching phosphoramidite. Org. Biomol. Chem., 2018, 16 (25), 4659-4664. DOI: 10.1039/c8ob00626a

3. Ellipilli, S.;  Palvai, S.; Ganesh, K. N., Fluorinated Peptide Nucleic Acids with Fluoroacetyl Side Chain Bearing 5-(F/CF3)-Uracil: Synthesis and Cell Uptake Studies. J. Org. Chem., 2016, 81 (15), 6364-73. DOI: 10.1021/acs.joc.6b01009

2. Ellipilli, S.; Vasudeva Murthy, R.; Ganesh, K. N., Perfluoroalkyl chain conjugation as a new tactic for enhancing cell permeability of peptide nucleic acids (PNAs) via reducing the nanoparticle size. Chem. Commun. (Camb), 2016, 52 (3), 521-4. DOI: 10.1039/c5cc05342k

1. Ellipilli, S.; Ganesh, K. N., Fluorous Peptide Nucleic Acids: PNA Analogues with Fluorine in Backbone (gamma-CF2-apg-PNA) Enhance Cellular Uptake. J. Org. Chem., 2015, 80 (18), 9185-91. DOI: 10.1021/acs.joc.5b01614

Chemical Biology Lab,

SRM university AP

bottom of page